A powerful explosion rocked central Havana on Friday morning, destroying parts of a luxury hotel and damaging nearby buildings just yards from the Cuban Capitol building.

At least 22 people were killed and dozens were injured, the president’s office said. More were missing. Among the dead were a pregnant woman and a child.

The devastating blast came as Cuba is trying to revive a tourism industry that is a key pillar of its fragile economy and that had been upended by the pandemic.

Videos and photos shared on social media showed ambulances rushing to the scene and much of the facade of the Hotel Saratoga destroyed. Rubble was piled on the street, and smoke billowed into the sky.